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Clobetasone Cream: Uses, Benefits, and Side Effects

Written by healthwords.ai's team of doctors and pharmacists based in UK | Updated: 25 Apr 2023 | 2 min read

Clobetasone butyrate 0.05% cream, also known by the brand name Eumovate, is a short-term steroid cream used to treat different causes of skin inflammation. The cream can be used to treat eczema, heat rash, and insect bites, as well as many other inflammatory skin conditions. There is also an ointment (greasier) version of clobetasone that is only available on prescription in the UK.

Who is it for?

Clobetasone is suitable for most adults and children over 12 years old. If you have a flare of eczema, the first step is usually to try a medical-grade moisturiser. If you have tried moisturising and seen no improvement, another option could be to try a steroid cream such as hydrocortisone or clobetasone. Clobetasone is more potent and should be used only after trying hydrocortisone first without satisfactory improvement. The cream aims to help inflammatory skin conditions by reducing inflammation and irritation for a short period of time. They are particularly useful at controlling short-term flares of skin and breaking the itch-scratch cycle. Steroid creams for nappy rash and other skin problems in children under 12 years old are only available on prescription.

How does it work?

Clobetasone butyrate 0.05% is a steroid (corticosteroid) and reduces the body's response to inflammatory reactions. By applying it directly to inflamed skin, the aim is to reduce inflammation in that area using the least amount of steroid possible.

Should anyone avoid taking it?

Like all medications, don’t take them if you have previously had an allergic reaction to the medication, or if you have other medications or medical conditions where you would normally discuss with your doctor or pharmacist before starting something new.

Clobetasone should be used for a maximum of 7 days in a row. It should be used on any children under the age of 12. It cannot be used on any open skin, and on any sensitive areas of the body, such as the face. Some people complain of a burning sensation when first applied, however, this sensation tends to disappear after a few days of applying.